We work towards understanding the mechanisms of cellular reprogramming and use this knowledge to generate human isogenic pluripotent stem cells and to clone animals at optimal efficiency.
Cellular Reprogramming Laboratory Jose CibelliCellular Reprogramming Laboratory Jose Cibelli
2024-06-14
We work towards understanding the mechanisms of cellular reprogramming that governs the transformation of a somatic cell into a pluripotent one. We identify regulatory genes and gene products that govern the state of pluripotency. We use this knowledge to generate human isogenic pluripotent stem cells and to improve the efficiency of somatic cell nuclear transfer.